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6FSO

Crystal Structure of TGT in complex with methyl({[5-(pyridin-3-yloxy)furan-2-yl]methyl})amine

Summary for 6FSO
Entry DOI10.2210/pdb6fso/pdb
DescriptorQueuine tRNA-ribosyltransferase, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (9 entities in total)
Functional Keywordstgt, trna, guanine exchange enzyme, protein interface, transferase
Biological sourceZymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Total number of polymer chains1
Total formula weight42833.05
Authors
Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2018-02-20, release date: 2019-03-20, Last modification date: 2024-01-17)
Primary citationHassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G.
Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies.
Chemmedchem, 15:324-337, 2020
Cited by
PubMed: 31808981
DOI: 10.1002/cmdc.201900604
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.449 Å)
Structure validation

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