6FO1

Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3.

Summary for 6FO1

Entry DOI	10.2210/pdb6fo1/pdb
EMDB information	4287
Descriptor	RuvB-like 1, RuvB-like 2, RNA polymerase II-associated protein 3, ... (4 entities in total)
Functional Keywords	r2tp, hsp90 co-chaperone, pih1d1, rpap3, ruvbl1-ruvbl2, chaperone
Biological source	Homo sapiens (Human) More
Total number of polymer chains	7
Total formula weight	382951.89
Authors	Martino, F.,Munoz-Hernandez, H.,Rodriguez, C.F.,Pearl, L.H.,Llorca, O. (deposition date: 2018-02-05, release date: 2018-04-04, Last modification date: 2019-12-11)
Primary citation	Martino, F.,Pal, M.,Munoz-Hernandez, H.,Rodriguez, C.F.,Nunez-Ramirez, R.,Gil-Carton, D.,Degliesposti, G.,Skehel, J.M.,Roe, S.M.,Prodromou, C.,Pearl, L.H.,Llorca, O. RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9:1501-1501, 2018 Cited by PubMed: 29662061 DOI: 10.1038/s41467-018-03942-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.57 Å)

Structure validation