6FMN
tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((2R,3S,4R,5R)-3,4-dihydroxy-5-methoxytetrahydrofuran-2-yl)methyl)amino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Summary for 6FMN
| Entry DOI | 10.2210/pdb6fmn/pdb |
| Related | 5JSV |
| Descriptor | Queuine tRNA-ribosyltransferase, GLYCEROL, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | co-crystallization, carbohydrates, transferase, transferase inhibitor |
| Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
| Total number of polymer chains | 1 |
| Total formula weight | 43665.19 |
| Authors | Nguyen, A.,Heine, A.,Klebe, G. (deposition date: 2018-02-01, release date: 2019-03-13, Last modification date: 2024-01-17) |
| Primary citation | Movsisyan, L.D.,Schafer, E.,Nguyen, A.,Ehrmann, F.R.,Schwab, A.,Rossolini, T.,Zimmerli, D.,Wagner, B.,Daff, H.,Heine, A.,Klebe, G.,Diederich, F. Sugar Acetonides are a Superior Motif for Addressing the Large, Solvent-Exposed Ribose-33 Pocket of tRNA-Guanine Transglycosylase. Chemistry, 24:9957-9967, 2018 Cited by PubMed: 29939431DOI: 10.1002/chem.201801756 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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