6FCM

Crystal structure of human PCNA

Summary for 6FCM

• Entry DOI: 10.2210/pdb6fcm/pdb
• Related: 1AXC
• Descriptor: Proliferating cell nuclear antigen (2 entities in total)
• Functional Keywords: proliferating cell nuclear antigen, nuclear protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 93294.87

Authors

Housset, D.,Frachet, P. (deposition date: 2017-12-20, release date: 2019-01-30, Last modification date: 2024-01-17)

• Primary citation: Ohayon, D.,De Chiara, A.,Dang, P.M.,Thieblemont, N.,Chatfield, S.,Marzaioli, V.,Burgener, S.S.,Mocek, J.,Candalh, C.,Pintard, C.,Tacnet-Delorme, P.,Renault, G.,Lagoutte, I.,Favier, M.,Walker, F.,Hurtado-Nedelec, M.,Desplancq, D.,Weiss, E.,Benarafa, C.,Housset, D.,Marie, J.C.,Frachet, P.,El-Benna, J.,Witko-Sarsat, V.; Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.; J.Exp.Med., 216:2669-2687, 2019; PubMed: 31492810; DOI: 10.1084/jem.20180371

Experimental method

X-RAY DIFFRACTION (2.8 Å)