6ETW

Crystal structure of KDM4D with tetrazolhydrazide compound 3

Summary for 6ETW

DescriptorLysine-specific demethylase 4D, ZINC ION, CHLORIDE ION, ... (9 entities in total)
Functional Keywordskdm4d, ligand binding, tetrazolylhydrazide, tetrazole, inhibitor design, cancer, epigenetics, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight40355.02
Authors
Malecki, P.H.,Link, A.,Weiss, M.S.,Heinemann, U. (deposition date: 2017-10-27, release date: 2019-02-20)
Primary citation
Malecki, P.H.,Link, A.,Weiss, M.S.,Heinemann, U.
Crystal Structure of KDM4D with tetrazolylhydrazide ligand Cn3
To be published,
Experimental method
X-RAY DIFFRACTION (1.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16670 1.8% 3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6etw
no rotation
Molmil generated image of 6etw
rotated about x axis by 90°
Molmil generated image of 6etw
rotated about y axis by 90°