6EDU

B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195

Summary for 6EDU

• Entry DOI: 10.2210/pdb6edu/pdb
• EMDB information: 7516 9038
• Descriptor: Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: hiv-1 env, broadly neutralizing antibodies, cryo-em, single particle analysis, viral protein-immune system complex, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 21
• Total formula weight: 601818.34

Authors

Barnes, C.O.,Bjorkman, P.J. (deposition date: 2018-08-11, release date: 2018-10-17, Last modification date: 2020-07-29)

• Primary citation: Wang, H.,Barnes, C.O.,Yang, Z.,Nussenzweig, M.C.,Bjorkman, P.J.; Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.; Cell Host Microbe, 24:579-592.e4, 2018; PubMed: 30308160; DOI: 10.1016/j.chom.2018.09.003

Experimental method

ELECTRON MICROSCOPY (4.06 Å)