6E0O

Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with pppA[3'-5']pA

Summary for 6E0O

DescriptorcGAS/DncV-like nucleotidyltransferase in E. coli homolog, RNA (5'-D(*(ATP))-R(P*A)-3'), MAGNESIUM ION, ... (4 entities in total)
Functional Keywordscgas, dncv, cyclic dinucleotide, nucleotide second messenger, nucleotidyltransferase, transferase, transferase-rna complex, transferase/rna
Biological sourceElizabethkingia meningoseptica ATCC 13253 = NBRC 12535
Total number of polymer chains3
Total molecular weight35770.41
Authors
Eaglesham, J.B.,Whiteley, A.T.,de Oliveira Mann, C.C.,Morehouse, B.R.,Nieminen, E.A.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J. (deposition date: 2018-07-06, release date: 2019-02-20, Last modification date: 2019-03-06)
Primary citation
Whiteley, A.T.,Eaglesham, J.B.,de Oliveira Mann, C.C.,Morehouse, B.R.,Lowey, B.,Nieminen, E.A.,Danilchanka, O.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J.
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Nature, 2019
PubMed: 30787435 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-019-0953-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.16850 0.4% 4.7% 0.00MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6e0o
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Molmil generated image of 6e0o
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Molmil generated image of 6e0o
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More Biological unit images

Molmil generated image of 6e0o
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Molmil generated image of 6e0o
rotated about x axis by 90°
Molmil generated image of 6e0o
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6e0o.pdb1.gz [148.14 KB])
Coordinate files for Biological unit (6e0o.pdb2.gz [4.88 KB])