Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase with Apcpp and Upnpp

Summary for 6E0L

DescriptorcGAS/DncV-like nucleotidyltransferase in E. coli homolog, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (5 entities in total)
Functional Keywordscgas, dncv, cyclic dinucleotide, nucleotide second messenger, nucleotidyltransferase, transferase
Biological sourceRhodothermus marinus SG0.5JP17-172
Total number of polymer chains1
Total molecular weight35904.69
Eaglesham, J.B.,Whiteley, A.T.,de Oliveira Mann, C.C.,Morehouse, B.R.,Nieminen, E.A.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J. (deposition date: 2018-07-06, release date: 2019-02-20, Last modification date: 2019-03-06)
Primary citation
Whiteley, A.T.,Eaglesham, J.B.,de Oliveira Mann, C.C.,Morehouse, B.R.,Lowey, B.,Nieminen, E.A.,Danilchanka, O.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J.
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Nature, 2019
PubMed: 30787435 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-019-0953-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21850 0.4% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6e0l
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Molmil generated image of 6e0l
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Molmil generated image of 6e0l
rotated about y axis by 90°