Trypanosoma brucei PRMT1 enzyme-prozyme heterotetrameric complex with AdoHcy

Summary for 6DNZ

DescriptorArginine N-methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
Functional Keywordsprotein arginine methyltransferase, prozyme, teterameric complex, prmt1, gene regulation
Biological sourceTrypanosoma brucei brucei TREU927
Total number of polymer chains4
Total molecular weight166171.03
Hashimoto, H.,Kafkova, L.,Jordan, K.,Read, L.K.,Debler, E.W. (deposition date: 2018-06-08, release date: 2019-06-12, Last modification date: 2020-02-12)
Primary citation
Hashimoto, H.,Kafkova, L.,Raczkowski, A.,Jordan, K.D.,Read, L.K.,Debler, E.W.
Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme).
J.Mol.Biol., 432:410-426, 2020
PubMed: 31726063 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2019.11.002
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22230 0.4% 6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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