6DJT

Structure of TYW1 with a lysine-pyruvate adduct bound

6DJT の概要

• エントリーDOI: 10.2210/pdb6djt/pdb
• 分子名称: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, IRON/SULFUR CLUSTER, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: s-adenosylmethionine radical enzymes, trna biosynthetic enzyme, metal binding protein
• 由来する生物種: Methanocaldococcus jannaschii (Methanococcus jannaschii)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40520.74

構造登録者

Grell, T.A.J.,Drennan, C.L. (登録日: 2018-05-26, 公開日: 2018-06-13, 最終更新日: 2023-11-29)

• 主引用文献: Grell, T.A.J.,Young, A.P.,Drennan, C.L.,Bandarian, V.; Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.; J. Am. Chem. Soc., 140:6842-6852, 2018; PubMed: 29792696; DOI: 10.1021/jacs.8b01493

実験手法

X-RAY DIFFRACTION (1.64 Å)