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6DH9

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602

Summary for 6DH9
Entry DOI10.2210/pdb6dh9/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, (5S)-5-({4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, nonanoic acid, ... (4 entities in total)
Functional Keywordsnuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-transcription inhibitor complex, transcription/transcription inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight62523.69
Authors
Shang, J.,Kojetin, D.J. (deposition date: 2018-05-18, release date: 2019-05-22, Last modification date: 2023-10-11)
Primary citationShang, J.,Kojetin, D.J.
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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