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6DFR

CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE

Summary for 6DFR
Entry DOI10.2210/pdb6dfr/pdb
DescriptorDIHYDROFOLATE REDUCTASE, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywordsoxido-reductase, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight18803.81
Authors
Bystroff, C.,Oatley, S.J.,Kraut, J. (deposition date: 1988-10-21, release date: 1990-07-15, Last modification date: 2024-03-13)
Primary citationBystroff, C.,Oatley, S.J.,Kraut, J.
Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
Biochemistry, 29:3263-3277, 1990
Cited by
PubMed: 2185835
DOI: 10.1021/bi00465a018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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