6DFO

Crystal structure of human GRP78 in complex with 8-bromoadenosine

Summary for 6DFO

DescriptorEndoplasmic reticulum chaperone BiP, 8-bromoadenosine (3 entities in total)
Functional Keywordsendoplasmic reticulum, unfolded protein response, nucleoside analog, chaperone
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight85003.7
Authors
Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W. (deposition date: 2018-05-15, release date: 2019-05-15)
Primary citation
Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W.
Crystal structure of human GRP78 in complex with 8-bromoadenosine
To be Published,
Experimental method
X-RAY DIFFRACTION (2.54 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2474 0.1% 3.5% 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6dfo
no rotation
Molmil generated image of 6dfo
rotated about x axis by 90°
Molmil generated image of 6dfo
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6dfo
no rotation
Molmil generated image of 6dfo
rotated about x axis by 90°
Molmil generated image of 6dfo
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6dfo.pdb1.gz [63.98 KB])
Coordinate files for Biological unit (6dfo.pdb2.gz [63.81 KB])