6DFC

Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) with a T-to-U substitution

Summary for 6DFC

Related6DF5 6DF8 6DF9 6DFA 6DFB
DescriptorTranscriptional regulator Kaiso, DNA (5'-D(*TP*GP*CP*TP*TP*CP*UP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*AP*GP*AP*AP*GP*CP*A)-3'), ... (6 entities in total)
Functional Keywordsdna methylation, zinc finger, transcriptional regulator, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (Human)
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Total number of polymer chains3
Total molecular weight27466.61
Authors
Nikolova, E.N.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E. (deposition date: 2018-05-14, release date: 2019-05-22)
Primary citation
Nikolova, E.N.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E.
A conformational switch at the zinc finger protein Kaiso directs recognitions of specific and methylated DNA
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.208200 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution