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6DEB

Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni

Summary for 6DEB
Entry DOI10.2210/pdb6deb/pdb
DescriptorBifunctional protein FolD, GUANINE, POTASSIUM ION, ... (9 entities in total)
Functional Keywordsmthfdc, alpha-beta-fold, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase
Biological sourceCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Total number of polymer chains2
Total formula weight63255.77
Authors
Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Grimshaw, S.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-05-11, release date: 2018-05-23, Last modification date: 2023-10-11)
Primary citationKim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Grimshaw, S.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID)
Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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