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6DDG

Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6

Summary for 6DDG
Entry DOI10.2210/pdb6ddg/pdb
Related6DDD
EMDB information7867 7870
Descriptor50S ribosomal protein L19, 50S ribosomal protein L28, 50S ribosomal protein L29, ... (28 entities in total)
Functional Keywordsantibiotic complex, linezolid, oxazolidinone, 50s, ribosome, ribosome-antibiotic complex, ribosome/antibiotic
Biological sourceStaphylococcus aureus
More
Total number of polymer chains27
Total formula weight1306299.35
Authors
Belousoff, M.J.,Venugopal, H.,Bamert, R.S.,Lithgow, T. (deposition date: 2018-05-10, release date: 2019-03-20, Last modification date: 2019-12-18)
Primary citationBelousoff, M.J.,Venugopal, H.,Wright, A.,Seoner, S.,Stuart, I.,Stubenrauch, C.,Bamert, R.S.,Lupton, D.W.,Lithgow, T.
cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria.
ChemMedChem, 14:527-531, 2019
Cited by
PubMed: 30667174
DOI: 10.1002/cmdc.201900042
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

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