6DB9

Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer

Summary for 6DB9

• Entry DOI: 10.2210/pdb6db9/pdb
• Descriptor: RNA (60-MER), Fab-Heavy-Chain, Fab-Light-Chain, ... (5 entities in total)
• Functional Keywords: fluorescent aptamer, fab, dir, rna, rna-immune system complex, rna/immune system
• Biological source: synthetic construct; More
• Total number of polymer chains: 3
• Total formula weight: 67376.46

Authors

Shao, Y.,Shelke, S.A.,Laski, A.,Piccirilli, J.A. (deposition date: 2018-05-02, release date: 2018-11-14, Last modification date: 2023-10-04)

• Primary citation: Shelke, S.A.,Shao, Y.,Laski, A.,Koirala, D.,Weissman, B.P.,Fuller, J.R.,Tan, X.,Constantin, T.P.,Waggoner, A.S.,Bruchez, M.P.,Armitage, B.A.,Piccirilli, J.A.; Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.; Nat Commun, 9:4542-4542, 2018; PubMed: 30382099; DOI: 10.1038/s41467-018-06942-3

Experimental method

X-RAY DIFFRACTION (2.025 Å)