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6OEV

Structure of human Patched1 in complex with native Sonic Hedgehog

Replaces:  6D4J
Summary for 6OEV
Entry DOI10.2210/pdb6oev/pdb
EMDB information7796
DescriptorProtein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordstumor suppressor, hh, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight181903.48
Authors
Qi, X.,Li, X. (deposition date: 2019-03-27, release date: 2019-04-17, Last modification date: 2020-07-29)
Primary citationQi, X.,Schmiege, P.,Coutavas, E.,Wang, J.,Li, X.
Structures of human Patched and its complex with native palmitoylated sonic hedgehog.
Nature, 560:128-132, 2018
Cited by
PubMed: 29995851
DOI: 10.1038/s41586-018-0308-7
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.8 Å)
Structure validation

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