6CZK

Crystal structure of wild-type human pro-cathepsin H

Summary for 6CZK

• Entry DOI: 10.2210/pdb6czk/pdb
• Descriptor: Pro-cathepsin H, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: papain family cysteine peptidase, protein degradation in lysosome, inhibitory prodomain, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39445.32

Authors

Huang, X.,Hao, Y. (deposition date: 2018-04-09, release date: 2018-08-08, Last modification date: 2023-10-04)

• Primary citation: Hao, Y.,Purtha, W.,Cortesio, C.,Rui, H.,Gu, Y.,Chen, H.,Sickmier, E.A.,Manzanillo, P.,Huang, X.; Crystal structures of human procathepsin H.; PLoS ONE, 13:e0200374-e0200374, 2018; PubMed: 30044821; DOI: 10.1371/journal.pone.0200374

Experimental method

X-RAY DIFFRACTION (2.001 Å)