6CSN

Crystal structure of the designed light-gated anion channel iC++ at pH8.5

Summary for 6CSN

• Entry DOI: 10.2210/pdb6csn/pdb
• Descriptor: iC++, RETINAL, OLEIC ACID, ... (5 entities in total)
• Functional Keywords: rhodopsin, channelrhodopsin, anion channel, optogenetics, membrane protein
• Biological source: Chlamydomonas reinhardtii
• Total number of polymer chains: 1
• Total formula weight: 33645.73

Authors

Kato, H.E.,Kim, Y.,Yamashita, K.,Kobilka, B.K.,Deisseroth, K. (deposition date: 2018-03-21, release date: 2018-09-05, Last modification date: 2023-10-04)

• Primary citation: Kato, H.E.,Kim, Y.S.,Paggi, J.M.,Evans, K.E.,Allen, W.E.,Richardson, C.,Inoue, K.,Ito, S.,Ramakrishnan, C.,Fenno, L.E.,Yamashita, K.,Hilger, D.,Lee, S.Y.,Berndt, A.,Shen, K.,Kandori, H.,Dror, R.O.,Kobilka, B.K.,Deisseroth, K.; Structural mechanisms of selectivity and gating in anion channelrhodopsins.; Nature, 561:349-354, 2018; PubMed: 30158697; DOI: 10.1038/s41586-018-0504-5

Experimental method

X-RAY DIFFRACTION (2.9 Å)