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6CRH

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP

Summary for 6CRH
Entry DOI10.2210/pdb6crh/pdb
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (8 entities in total)
Functional Keywordsdna binding protein, transferase, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight48342.11
Authors
Koag, M.-C.,Lee, S. (deposition date: 2018-03-17, release date: 2019-03-20, Last modification date: 2024-03-13)
Primary citationKou, Y.,Koag, M.C.,Lee, S.
Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
Molecules, 24:-, 2019
Cited by
PubMed: 31569643
DOI: 10.3390/molecules24193507
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.327 Å)
Structure validation

217705

PDB entries from 2024-03-27

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