Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6CNQ

MBD2 in complex with methylated DNA

Replaces:  6C2E
Summary for 6CNQ
Entry DOI10.2210/pdb6cnq/pdb
DescriptorMethyl-CpG-binding domain protein 2, DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywordsdna methylation, dna binding, structural genomics, structural genomics consortium, sgc, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus : Q9UBB5
Total number of polymer chains6
Total formula weight32292.02
Authors
Liu, K.,Xu, C.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-03-08, release date: 2018-03-28, Last modification date: 2023-10-04)
Primary citationLiu, K.,Xu, C.,Lei, M.,Yang, A.,Loppnau, P.,Hughes, T.R.,Min, J.
Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293:7344-7354, 2018
Cited by
PubMed: 29567833
DOI: 10.1074/jbc.RA118.001785
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.151 Å)
Structure validation

218853

数据于2024-04-24公开中

PDB statisticsPDBj update infoContact PDBjnumon