6CK9

Crystal Structure of HIV-1 ConC_Base0 Prefusion Env Trimer in Complex with Human Antibody Fragment 3H109L and 35O22 variants at 3.5 Angstrom

Summary for 6CK9

• Entry DOI: 10.2210/pdb6ck9/pdb
• Descriptor: gp41 ectodomain of Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: hiv-1 envelope fusion glycoprotein, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 155614.33

Authors

Lai, Y.-T.,Kwong, P.D. (deposition date: 2018-02-27, release date: 2018-04-25, Last modification date: 2022-03-23)

• Primary citation: Rutten, L.,Lai, Y.T.,Blokland, S.,Truan, D.,Bisschop, I.J.M.,Strokappe, N.M.,Koornneef, A.,van Manen, D.,Chuang, G.Y.,Farney, S.K.,Schuitemaker, H.,Kwong, P.D.,Langedijk, J.P.M.; A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers.; Cell Rep, 23:584-595, 2018; PubMed: 29642014; DOI: 10.1016/j.celrep.2018.03.061

Experimental method

X-RAY DIFFRACTION (2.714 Å)