6CDX

High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin

Summary for 6CDX

Related2N8B 2N8C
Descriptorcystine knot (fluoropropylated) (2 entities in total)
Functional Keywordscysteine, disulfides, alpha-5 beta-6 integrin binding epitope, cancer imaging, protein binding
Biological sourceMomordica cochinchinensis (Spiny bitter cucumber)
Total number of polymer chains2
Total molecular weight7833
Authors
Kimura, R.,Nix, J.,Bongura, C.,Chakraborti, S.,Gambhir, S.,Filipp, F.V. (deposition date: 2018-02-09, release date: 2019-08-14)
Primary citation
Kimura, R.,Gambhir, S.S.
High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin
To be Published,
Experimental method
X-RAY DIFFRACTION (1 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.222100 1.8% 11.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution