6CCH
NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state)
Summary for 6CCH
| Entry DOI | 10.2210/pdb6cch/pdb |
| NMR Information | BMRB: 30401 |
| Descriptor | Apolipoprotein A-I, GTPase KRas, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total) |
| Functional Keywords | protein-bilayer-compound complex, membrane protein-oncoprotein complex, membrane protein/oncoprotein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 131301.85 |
| Authors | Fang, Z.,Marshall, C.B.,Nishikawa, T.,Gossert, A.D.,Jansen, J.M.,Jahnke, W.,Ikura, M. (deposition date: 2018-02-07, release date: 2018-08-29, Last modification date: 2023-06-14) |
| Primary citation | Fang, Z.,Marshall, C.B.,Nishikawa, T.,Gossert, A.D.,Jansen, J.M.,Jahnke, W.,Ikura, M. Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25:1327-1336.e4, 2018 Cited by PubMed: 30122370DOI: 10.1016/j.chembiol.2018.07.009 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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