6C1O

FGFR1 kinase domain complexed with FIIN-1

6C1O の概要

• エントリーDOI: 10.2210/pdb6c1o/pdb
• 分子名称: Fibroblast growth factor receptor 1, N-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)prop-2-enamide, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72116.49

構造登録者

Kalyukina, M.,Yosaatmadja, Y.,Smaill, J.B.,Squire, C.J. (登録日: 2018-01-05, 公開日: 2019-01-16, 最終更新日: 2023-10-04)

• 主引用文献: Kalyukina, M.,Yosaatmadja, Y.,Patterson, A.V.,Smaill, J.B.,Squire, C.J.; A new class of FGFR1 inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.29 Å)