6BQB

MGG4 Fab in complex with peptide

Summary for 6BQB

Entry DOI	10.2210/pdb6bqb/pdb
Descriptor	MGG4 Fab light chain, MGG4 Fab heavy chain, N-terminal junction peptide, ... (5 entities in total)
Functional Keywords	human fab fragment peptide binding plasmodium falciparum circumsporozoite protein, immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	49943.60
Authors	Oyen, D.,Tan, J.,Lanzavecchia, A.,Wilson, I.A. (deposition date: 2017-11-27, release date: 2018-03-07, Last modification date: 2018-04-25)
Primary citation	Tan, J.,Sack, B.K.,Oyen, D.,Zenklusen, I.,Piccoli, L.,Barbieri, S.,Foglierini, M.,Fregni, C.S.,Marcandalli, J.,Jongo, S.,Abdulla, S.,Perez, L.,Corradin, G.,Varani, L.,Sallusto, F.,Sim, B.K.L.,Hoffman, S.L.,Kappe, S.H.I.,Daubenberger, C.,Wilson, I.A.,Lanzavecchia, A. A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nat. Med., 24:401-407, 2018 Cited by PubMed: 29554084 DOI: 10.1038/nm.4513 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.769 Å)

Structure validation