6BLF

PDE2 complexed with 2-[6-fluoro-8-methylsulfonyl-9-[(1R)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid

Summary for 6BLF

• Entry DOI: 10.2210/pdb6blf/pdb
• Descriptor: cGMP-dependent 3',5'-cyclic phosphodiesterase, [(1S)-6-fluoro-8-(methylsulfonyl)-9-{(1R)-1-[4-(trifluoromethyl)phenyl]ethyl}-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetic acid, ZINC ION, ... (5 entities in total)
• Functional Keywords: phosphodiesterase, inhibitor, complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 88564.03

Authors

Su, H.P. (deposition date: 2017-11-10, release date: 2018-11-14, Last modification date: 2024-03-13)

• Primary citation: Su, H.P.; Hydrolase complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.11 Å)