6AQB
Structure of the SH3 domain of MLK3 bound to peptide generated from phage display
Summary for 6AQB
Entry DOI | 10.2210/pdb6aqb/pdb |
Descriptor | Chimera protein of MLK3-SH3 and MIP (E.C.2.7.11.25), 1,2-ETHANEDIOL, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | mlk3, sh3, phage display, signalling protein, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 15954.36 |
Authors | Kall, S.K.,Lavie, A. (deposition date: 2017-08-19, release date: 2018-07-04, Last modification date: 2024-03-13) |
Primary citation | Kokoszka, M.E.,Kall, S.L.,Khosla, S.,McGinnis, J.E.,Lavie, A.,Kay, B.K. Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3. J. Biol. Chem., 293:13553-13565, 2018 Cited by PubMed: 29980598DOI: 10.1074/jbc.RA117.000262 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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