6ANV

Crystal structure of anti-CRISPR protein AcrF1

6ANV の概要

• エントリーDOI: 10.2210/pdb6anv/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900010
• 分子名称: anti-CRISPR protein AcrF1 fused with C-terminal MBP tag, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total)
• 機能のキーワード: type i-f crispr-cas system: csy cascade: structure: anti-crispr protein: inhibition of csy complex: genome editing tool, immune system
• 由来する生物種: Pseudomonas phage JBD30; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102897.75

構造登録者

Yang, H.,Patel, D.J. (登録日: 2017-08-14, 公開日: 2017-10-25, 最終更新日: 2023-10-04)

• 主引用文献: Guo, T.W.,Bartesaghi, A.,Yang, H.,Falconieri, V.,Rao, P.,Merk, A.,Eng, E.T.,Raczkowski, A.M.,Fox, T.,Earl, L.A.,Patel, D.J.,Subramaniam, S.; Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.; Cell, 171:414-426.e12, 2017; PubMed: 28985564; DOI: 10.1016/j.cell.2017.09.006

実験手法

X-RAY DIFFRACTION (2.265 Å)