6AJF

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis

Summary for 6AJF

Entry DOI	10.2210/pdb6ajf/pdb
Descriptor	Drug exporters of the RND superfamily-like protein,Endolysin, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside (3 entities in total)
Functional Keywords	membrane protein, transporter, rnd family, cell wall biosynthesis, drug target, hydrolase
Biological source	Mycobacterium smegmatis str. MC2 155 More
Total number of polymer chains	1
Total formula weight	106430.40
Authors	Zhang, B.,Li, J.,Yang, X.L.,Wu, L.J.,Yang, H.T.,Rao, Z.H. (deposition date: 2018-08-27, release date: 2018-12-26, Last modification date: 2024-03-27)
Primary citation	Zhang, B.,Li, J.,Yang, X.,Wu, L.,Zhang, J.,Yang, Y.,Zhao, Y.,Zhang, L.,Yang, X.,Yang, X.,Cheng, X.,Liu, Z.,Jiang, B.,Jiang, H.,Guddat, L.W.,Yang, H.,Rao, Z. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176:636-648.e13, 2019 Cited by PubMed: 30682372 DOI: 10.1016/j.cell.2019.01.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.698 Å)

Structure validation