6AJA

Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADPH, alpha-ketoglutarate and ca2+

6AJA の概要

• エントリーDOI: 10.2210/pdb6aja/pdb
• 分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: trypanosoma brucei, glycosome, metabolism, isocitrate dehydrogenase, oxidoreductase
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 190814.77

構造登録者

Wang, X.,Inaoka, D.K.,Shiba, T.,Balogun, E.O.,Ziebart, N.,Allman, S.,Watanabe, Y.,Nozaki, T.,Boshart, M.,Bringaud, F.,Harada, S.,Kita, K. (登録日: 2018-08-27, 公開日: 2019-08-28, 最終更新日: 2023-11-22)

• 主引用文献: Wang, X.,Inaoka, D.K.,Shiba, T.,Balogun, E.O.,Ziebart, N.,Allman, S.,Watanabe, Y.,Nozaki, T.,Boshart, M.,Bringaud, F.,Harada, S.,Kita, K.; Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+); To Be Published,

実験手法

X-RAY DIFFRACTION (2.85 Å)