6AHF

CryoEM Reconstruction of Hsp104 N728A Hexamer

Summary for 6AHF

• Entry DOI: 10.2210/pdb6ahf/pdb
• EMDB information: 9625
• Descriptor: Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
• Functional Keywords: chaperone, hsp, holdase
• Biological source: Saccharomyces cerevisiae S288c (Baker's yeast)
• Total number of polymer chains: 6
• Total formula weight: 615925.11

Authors

Zhang, X.,Zhang, L.,Zhang, S. (deposition date: 2018-08-17, release date: 2019-02-13, Last modification date: 2019-04-10)

• Primary citation: Zhang, X.,Zhang, S.,Zhang, L.,Lu, J.,Zhao, C.,Luo, F.,Li, D.,Li, X.,Liu, C.; Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.; J. Biol. Chem., 294:4956-4965, 2019; PubMed: 30718279; DOI: 10.1074/jbc.RA118.005980

Experimental method

ELECTRON MICROSCOPY (6.78 Å)