6AGF

Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1

Summary for 6AGF

Entry DOI	10.2210/pdb6agf/pdb
EMDB information	9617
Descriptor	Sodium channel protein type 4 subunit alpha, Sodium channel subunit beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	sodium channel, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	244299.03
Authors	Pan, X.J.,li, Z.Q.,Zhou, Q.,Shen, H.Z.,Wu, K.,Huang, X.S.,Chen, J.F.,Zhang, J.R.,Zhu, X.C.,Lei, J.L.,Xiong, W.,Gong, H.P.,Xiao, B.L.,Yan, N. (deposition date: 2018-08-11, release date: 2018-10-10, Last modification date: 2020-07-29)
Primary citation	Pan, X.,Li, Z.,Zhou, Q.,Shen, H.,Wu, K.,Huang, X.,Chen, J.,Zhang, J.,Zhu, X.,Lei, J.,Xiong, W.,Gong, H.,Xiao, B.,Yan, N. Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta 1. Science, 362:-, 2018 Cited by PubMed: 30190309 DOI: 10.1126/science.aau2486 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation