6AEC

Binary complex of human DNA Polymerase Mu with MnATP

Summary for 6AEC

Entry DOI	10.2210/pdb6aec/pdb
Descriptor	DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	dna polymerase mu, dna break repair, transferase-rntp complex, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	41247.87
Authors	Chang, Y.K.,Wu, W.J.,Tsai, M.D. (deposition date: 2018-08-04, release date: 2019-05-29, Last modification date: 2023-11-22)
Primary citation	Chang, Y.K.,Huang, Y.P.,Liu, X.X.,Ko, T.P.,Bessho, Y.,Kawano, Y.,Maestre-Reyna, M.,Wu, W.J.,Tsai, M.D. Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141:8489-8502, 2019 Cited by PubMed: 31067051 DOI: 10.1021/jacs.9b01741 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation