6A4O

HEWL crystals soaked in 2.5M GuHCl for 20 minutes

Replaces:  5H6C

Summary for 6A4O

DescriptorLysozyme C, GUANIDINE, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsprotein unfolding, chemical denaturant, guanidine, lysozyme, hydrolase
Biological sourceGallus gallus (Chicken)
Total number of polymer chains1
Total molecular weight14884.03
Authors
Tushar, R.,Kini, R.M.,Koh, C.Y.,Hosur, M.V. (deposition date: 2018-06-20, release date: 2019-03-13)
Primary citation
Raskar, T.,Koh, C.Y.,Niebling, S.,Kini, R.M.,Hosur, M.V.
X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122:903-913, 2019
PubMed: 30412756 (PDB entries with the same primary citation)
DOI: 10.1016/j.ijbiomac.2018.11.023
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21660 1.0% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6a4o
no rotation
Molmil generated image of 6a4o
rotated about x axis by 90°
Molmil generated image of 6a4o
rotated about y axis by 90°