6A3W

Complex structure of 4-1BB and utomilumab

Summary for 6A3W

• Entry DOI: 10.2210/pdb6a3w/pdb
• Descriptor: utomilumab VH, utomilumab VL, Tumor necrosis factor receptor superfamily member 9, ... (5 entities in total)
• Functional Keywords: complex structure, 4-1bb, angonist monoclonal antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 167968.02

Authors

Li, Y.,Tan, S.,Zhang, C.,Chai, Y.,Qi, J.,Tien, P.,Gao, S.,Gao, G.F. (deposition date: 2018-06-17, release date: 2018-10-10, Last modification date: 2023-11-22)

• Primary citation: Li, Y.,Tan, S.,Zhang, C.,Chai, Y.,He, M.,Zhang, C.W.,Wang, Q.,Tong, Z.,Liu, K.,Lei, Y.,Liu, W.J.,Liu, Y.,Tian, Z.,Cao, X.,Yan, J.,Qi, J.,Tien, P.,Gao, S.,Gao, G.F.; Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.; Cell Rep, 25:909-920.e4, 2018; PubMed: 30355497; DOI: 10.1016/j.celrep.2018.09.073

Experimental method

X-RAY DIFFRACTION (2 Å)