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6X96

Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding variable domain

Summary for 6X96
Entry DOI10.2210/pdb6x96/pdb
EMDB information22102 22103 22104
DescriptorBG505 HIV-1 Env gp120, BG505 HIV-1 Env gp41, monoclonal antibody 10A fragment antigen binding heavy chain, ... (7 entities in total)
Functional Keywordshiv-1, env, glycan hole, antibody, vaccine design, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
More
Total number of polymer chains12
Total formula weight390022.20
Authors
Ozorowski, G.,Cottrell, C.A.,Ward, A.B. (deposition date: 2020-06-02, release date: 2021-12-08)
Primary citationOzorowski, G.,Cottrell, C.A.,de Val, N.,Scaringi, N.,Polveroni, T.M.,Ward, A.B.
Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

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