6WXL
Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer
Summary for 6WXL
Entry DOI | 10.2210/pdb6wxl/pdb |
EMDB information | 21961 |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 1D12 Light chain, ... (5 entities in total) |
Functional Keywords | vrc, immune system, vrc315, group 2, fab |
Biological source | Influenza A virus (A/Shanghai/JS01/2013(H7N9)) More |
Total number of polymer chains | 12 |
Total formula weight | 329854.32 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2020-05-11, release date: 2021-06-09, Last modification date: 2022-06-22) |
Primary citation | Cheung, C.S.,Gorman, J.,Andrews, S.F.,Rawi, R.,Reveiz, M.,Shen, C.H.,Wang, Y.,Harris, D.R.,Nazzari, A.F.,Olia, A.S.,Raab, J.,Teng, I.T.,Verardi, R.,Wang, S.,Yang, Y.,Chuang, G.Y.,McDermott, A.B.,Zhou, T.,Kwong, P.D. Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite. Structure, 2022 Cited by PubMed: 35489332DOI: 10.1016/j.str.2022.04.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.76 Å) |
Structure validation
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