6W2B
Anomalous bromine signal reveals the position of Br-paroxetine complexed with the serotonin transporter at the central site
Summary for 6W2B
Entry DOI | 10.2210/pdb6w2b/pdb |
Descriptor | Sodium-dependent serotonin transporter, 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, ... (5 entities in total) |
Functional Keywords | antidepressant, complex, transporter, antibody, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 110887.10 |
Authors | Coleman, J.A.,Navratna, V.,Yang, D. (deposition date: 2020-03-05, release date: 2020-03-25, Last modification date: 2023-10-18) |
Primary citation | Coleman, J.A.,Navratna, V.,Antermite, D.,Yang, D.,Bull, J.A.,Gouaux, E. Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9:-, 2020 Cited by PubMed: 32618269DOI: 10.7554/eLife.56427 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.7 Å) |
Structure validation
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