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6VWB

Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81

Summary for 6VWB
Entry DOI10.2210/pdb6vwb/pdb
NMR InformationBMRB: 30725
DescriptorCrossover junction endonuclease MUS81 (1 entity in total)
Functional Keywordsdna repair, branched dna structure, dna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight10618.41
Authors
Payliss, B.,Houliston, S.,Lemak, A.,Arrowsmith, C.H.,Wyatt, H.D.M. (deposition date: 2020-02-19, release date: 2021-02-24, Last modification date: 2023-06-14)
Primary citationPayliss, B.,Houliston, S.,Lemak, A.,Arrowsmith, C.H.,Wyatt, H.D.M.
Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease
Cell Rep, 41:-, 2022
Experimental method
SOLUTION NMR
Structure validation

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