6UUM
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-Cys100aA)
Summary for 6UUM
Entry DOI | 10.2210/pdb6uum/pdb |
Related | 6UTK |
Descriptor | B11 Fab Light Chain, B11 DSS Fab Heavy Chain, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | v3 glycan supersite, human antibody, immune system, anti-hiv1 neutralizing antibody, viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 101775.26 |
Authors | Kumar, S.,Wilson, I.A. (deposition date: 2019-10-30, release date: 2020-09-23, Last modification date: 2023-10-11) |
Primary citation | Kumar, S.,Ju, B.,Shapero, B.,Lin, X.,Ren, L.,Zhang, L.,Li, D.,Zhou, Z.,Feng, Y.,Sou, C.,Mann, C.J.,Hao, Y.,Sarkar, A.,Hou, J.,Nunnally, C.,Hong, K.,Wang, S.,Ge, X.,Su, B.,Landais, E.,Sok, D.,Zwick, M.B.,He, L.,Zhu, J.,Wilson, I.A.,Shao, Y. A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6:-, 2020 Cited by PubMed: 32938661DOI: 10.1126/sciadv.abb1328 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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