6UG7
Complex of ch28/11 Fab and SSEA-4 (tetragonal form)
Summary for 6UG7
Entry DOI | 10.2210/pdb6ug7/pdb |
Descriptor | ch28/11 Fab light chain, ch28/11 Fab heavy chain, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | immunoglobulin, chimeric antibody, antigen binding fragment, ssea-4, complex, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48039.21 |
Authors | Soliman, C.,Ramsland, P.A. (deposition date: 2019-09-26, release date: 2019-12-18, Last modification date: 2023-10-11) |
Primary citation | Soliman, C.,Chua, J.X.,Vankemmelbeke, M.,McIntosh, R.S.,Guy, A.J.,Spendlove, I.,Durrant, L.G.,Ramsland, P.A. The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody. J.Biol.Chem., 295:1009-1020, 2020 Cited by PubMed: 31831622DOI: 10.1074/jbc.RA119.011518 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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