6TKV
Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan
Summary for 6TKV
Entry DOI | 10.2210/pdb6tkv/pdb |
Descriptor | Alpha-(1,6)-fucosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | glycosyltransferase, sugar nucleotide, acceptor substrate, catalysis, sugar binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 111371.82 |
Authors | Garcia-Garcia, A.,Ceballos-Laita, L.,Serna, L.,Artschwager, R.,Reichardt, N.C.,Corzana, F.,Hurtado-Guerrero, R. (deposition date: 2019-11-29, release date: 2020-01-29, Last modification date: 2024-01-24) |
Primary citation | Garcia-Garcia, A.,Ceballos-Laita, L.,Serna, S.,Artschwager, R.,Reichardt, N.C.,Corzana, F.,Hurtado-Guerrero, R. Structural basis for substrate specificity and catalysis of alpha 1,6-fucosyltransferase. Nat Commun, 11:973-973, 2020 Cited by PubMed: 32080177DOI: 10.1038/s41467-020-14794-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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