6SNY
Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR
Summary for 6SNY
Entry DOI | 10.2210/pdb6sny/pdb |
Descriptor | Synthetic EPCR binding protein, Endothelial protein C receptor, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | pfemp1 epcr vaccine immunogen, immune system |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 64103.24 |
Authors | Barber, N.M.,Higgins, M.K. (deposition date: 2019-08-27, release date: 2019-09-04, Last modification date: 2021-01-20) |
Primary citation | Barber, N.M.,Lau, C.K.Y.,Turner, L.,Watson, G.,Thrane, S.,Lusingu, J.P.A.,Lavstsen, T.,Higgins, M.K. Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein. Msphere, 6:-, 2021 Cited by PubMed: 33408232DOI: 10.1128/mSphere.01081-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.11 Å) |
Structure validation
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