6RTI
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g
Summary for 6RTI
Entry DOI | 10.2210/pdb6rti/pdb |
Descriptor | Glutamate carboxypeptidase 2, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... (12 entities in total) |
Functional Keywords | glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; aptamer, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 98360.82 |
Authors | Motlova, L.,Kolenko, P.,Barinka, C. (deposition date: 2019-05-24, release date: 2020-06-10, Last modification date: 2024-01-24) |
Primary citation | Ptacek, J.,Zhang, D.,Qiu, L.,Kruspe, S.,Motlova, L.,Kolenko, P.,Novakova, Z.,Shubham, S.,Havlinova, B.,Baranova, P.,Chen, S.J.,Zou, X.,Giangrande, P.,Barinka, C. Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer. Nucleic Acids Res., 48:11130-11145, 2020 Cited by PubMed: 32525981DOI: 10.1093/nar/gkaa494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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