6Q8F

Nterminal domain of human SMU1

6Q8F の概要

• エントリーDOI: 10.2210/pdb6q8f/pdb
• 分子名称: WD40 repeat-containing protein SMU1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: splicing factor, splicing
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115592.29

構造登録者

Tengo, L.,Le Corre, L.,Fournier, G.,Ashraf, U.,Busca, P.,Rameix-Welti, M.-A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.-O.,Pietrancosta, N.,Naffakh, N.,McCarthy, A.A.,Crepin, T. (登録日: 2018-12-14, 公開日: 2019-05-22, 最終更新日: 2019-06-12)

• 主引用文献: Ashraf, U.,Tengo, L.,Le Corre, L.,Fournier, G.,Busca, P.,McCarthy, A.A.,Rameix-Welti, M.A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.O.,Pietrancosta, N.,Crepin, T.,Naffakh, N.; Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.; Proc.Natl.Acad.Sci.USA, 116:10968-10977, 2019; PubMed: 31076555; DOI: 10.1073/pnas.1901214116

実験手法

X-RAY DIFFRACTION (1.9 Å)