6OZ2
Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core.
Summary for 6OZ2
Entry DOI | 10.2210/pdb6oz2/pdb |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, N49P6 antibody Fab heavy chain, N49P6 antibody Fab light chain, ... (5 entities in total) |
Functional Keywords | hiv-1, vrc01-class antibody, cd4 binding site, clade a/e 93th057 gp120, viral protein-immune system complex, n49p6, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 88485.88 |
Authors | Tolbert, W.D.,Pazgier, M. (deposition date: 2019-05-15, release date: 2020-08-19, Last modification date: 2024-01-10) |
Primary citation | Tolbert, W.D.,Nguyen, D.N.,Tehrani, Z.R.,Sajadi, M.M.,Pazgier, M. Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, :e0127421-e0127421, 2021 Cited by PubMed: 34281393DOI: 10.1128/mBio.01274-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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