6OWM

Horse liver F93W alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol

Summary for 6OWM

Entry DOI	10.2210/pdb6owm/pdb
Related	1A71 1AXE 4DWV 4ng5 5kcp 6o91
Descriptor	Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywords	alcohol dehydrogenase, nad, pentafluorobenzyl alcohol, phe93 to trp substitution, horse liver e enzyme, oxidoreductase
Biological source	Equus caballus (Horse)
Total number of polymer chains	2
Total formula weight	82123.81
Authors	Plapp, B.V. (deposition date: 2019-05-10, release date: 2019-05-22, Last modification date: 2023-10-11)
Primary citation	Kim, K.,Plapp, B.V. Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59:862-879, 2020 Cited by PubMed: 31994873 DOI: 10.1021/acs.biochem.9b01074 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation