6O4P
The crystal structure of the interleukin 11 alpha receptor
Summary for 6O4P
Entry DOI | 10.2210/pdb6o4p/pdb |
Descriptor | Interleukin-11 receptor subunit alpha, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cytokine, interleukin, receptor, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 78874.29 |
Authors | Aizel, K.,Metcalfe, R.D.,Griffin, M.D.W. (deposition date: 2019-02-28, release date: 2020-05-06, Last modification date: 2020-07-29) |
Primary citation | Metcalfe, R.D.,Aizel, K.,Zlatic, C.O.,Nguyen, P.M.,Morton, C.J.,Lio, D.S.,Cheng, H.C.,Dobson, R.C.J.,Parker, M.W.,Gooley, P.R.,Putoczki, T.L.,Griffin, M.D.W. The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295:8285-8301, 2020 Cited by PubMed: 32332100DOI: 10.1074/jbc.RA119.012351 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.429 Å) |
Structure validation
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